Introduction to Enzalieva 40mg Capsule

Enzalieva 40mg Capsule contains the active compound enzalutamide which belongs to the class of medications called androgen receptor inhibitors. It is used to treat men with prostate cancer. It is suitable for treatment in men with high testosterone, where the treatments (hormonal therapy or testosterone-lowering surgery) that reduce testosterone no longer totally cure the malignancy. It is also suitable for treatment in metastatic cases where the cancer has spread from the prostate to other parts and reacts to hormone therapy or surgery to reduce testosterone levels. It is also used in cases of Prostate cancer that is responsive to castration( surgical removal of testicles) but is not metastatic, with a high chance of metastasis and a biochemical recurrence.

It is not recommended to take Enzalieva 40mg Capsule if you are allergic to active compounds or any other ingredients of this medicine. It is not recommended for use in children and adolescents below the age of 18. Men are advised to use effective contraceptive methods during the therapy and 3 months after the treatment since it has the ability to harm the developing foetus. Inform your doctor if you are pregnant or planning to get pregnant to know about effective contraceptive methods. It is recommended to test your bone density during the treatment. 

Before initiating the treatment, inform your physician if you have any infections, kidney, heart or liver problems. Patients who have ischemic heart disease are closely monitored for risk factors.  Inform your doctor right away if you experience a seizure, headache that is getting worse, disorientation, blindness, or any other vision issues. It is necessary to inform your physician about all the medicines, over the counter drugs, vitamin and herbal supplements you are taking before the start of therapy.  

Uses of Enzalieva 40mg Capsule

• Prostate cancer resistant to other treatments
• Metastatic prostate cancer reacts to hormone therapy or surgery to reduce testosterone levels
• Non metastatic prostate cancer with a high chance of spread and recurrence.

Therapeutic Effects of Enzalieva 40mg Capsule

Enzalieva 40mg Capsule medicine acts by blocking the activity of androgens hormone (such as testosterone) by binding with androgen receptors. Enzalieva 40mg Capsule prevents the Androgen receptor from moving to its new site, which further lowers AR-mediated transcriptional activity and stops the growth of tumor cells. Enzalieva 40mg Capsule inhibits the AR complex's ability to bind to DNA, which stops the transcriptional activation of AR target genes. As a result, it reduces testosterone levels and halts the growth and division of prostate cancer cells.

Interaction with other drugs:

Interaction of Enzalieva 40mg Capsule with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Enzalieva 40mg Capsule and reduce effectiveness by causing undesirable side effects. 

More Information about Enzalieva 40mg Capsule

• Enzalieva 40mg Capsule should be stored at room temperature between 20°C and 25°C (68°F and 77°F).
• It should be kept dry and protected from light and moisture.
• The capsules should be kept in the original container with the cap tightly closed..
• Keep it out of reach from children and pets.
• It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.

How to consume Enzalieva 40mg Capsule

Enzalieva 40mg Capsule is usually taken orally, with or without food. The capsules should be swallowed whole with a glass of water and not crushed, chewed or broken.

The dosage and frequency of Enzalieva 40mg Capsule will depend on various factors, including the patient's age, weight, overall health, and the type and stage of cancer being treated. It's important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first. Pregnant or potentially pregnant women shouldn't handle broken or damaged Xtandi tablets without wearing gloves or other protective gear.

If a dose is missed, it should be taken as soon as possible unless it's within 6 hours of the next scheduled dose. In that case, the missed dose should be skipped and the regular dosing schedule resumed. It's important not to take a double dose of abemaciclib to make up for a missed dose.