| Description | BORTLIEVA 2 mg contains Bortezomib, a reversible proteasome inhibitor that inhibits the 26S proteasome. This leads to accumulation of misfolded proteins, disruption of cellular homeostasis, and apoptosis of malignant plasma cells. It is a key drug in multiple myeloma therapy. |
| Uses | Bortezomib is indicated for: 1. Multiple Myeloma 2. Mantle Cell Lymphoma (MCL) |
| Side Effects | Common side effects: • Peripheral neuropathy (dose-limiting) • Thrombocytopenia, anemia • Nausea, diarrhea, constipation • Fatigue Other side effects: • Herpes zoster reactivation • Hypotension Serious side effects: • Severe neuropathy • Heart failure (rare) • Pulmonary toxicity (rare) Antiviral prophylaxis (e.g., acyclovir) is recommended. |
| Dosage | Dosage is based on body surface area (BSA). Standard dose: • 1.3 mg/m² per dose Schedule: • IV or SC on Days 1, 4, 8, and 11 of a 21-day cycle 2 mg vial is commonly used for single-dose preparation. |
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Cobus Bester
Cobus Bester on Mar 03, 2023
Can’t wait to start mixin’ with this one! Irba-irr-Up-up-up-up-date your theme!
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